Master's Thesis in Retina Research
RPE Cell Function in Retinitis Pigmentosa
26.05.2024
Master's Thesis in Retina Research: RPE Cell Function in Retinitis Pigmentosa
Start Date: As soon as possible
Our research group is dedicated to studying degenerative retinal diseases, focusing on Retinitis Pigmentosa (RP). RP is an inherited disease characterized by the progressive loss of photoreceptors in the retina, ultimately leading to blindness. A key element in the development and progression of RP is the retinal pigment epithelium (RPE), which plays a crucial role in the health and function of photoreceptors.
As part of this master's thesis, primary RPE cells from mice will be generated and studied to better understand the cellular mechanisms leading to degeneration. The aim is to characterize the function, metabolism, and morphology of RPE cells in retinitis pigmentosa in detail These findings could provide valuable insights for the development of new therapeutic strategies.
Tasks:
- Generation and analysis of primary cell lines from mice
- Examination of the function, metabolism, and morphology of RPE cells in Retinitis Pigmentosa
- Application and learning of techniques such as cell culture, live cell imaging, qRT-PCR, Western Blot, and other molecular biology methods
Qualifications:
- Studies in Pharmaceutical Sciences, Biology, or related natural science disciplines
- A strong interest in modern microscopy techniques, molecular biology, and biochemical methods
- Teamwork skills and high motivation
We offer:
- A diverse project in an innovative and well-equipped laboratory
- Excellent training and supervision in a motivated, international team
Prof. Dr. Susanne Koch and Felia Haffelder (PhD student)
Ludwig-Maximilians-University Munich
Pharmacology for natural science
Butenandtstr. 7 81377 München
We are looking forward to receiving your application via email: felia.haffelder@cup.uni-muenchen.de